Expression of MMP1, MMP3, and TIMP1 in intervertebral discs under simulated overload and microgravity conditions

Abstract Objective This study aims to investigate changes in matrix metalloproteinase (MMP) and tissue inhibitor of metalloproteinase (TIMP) levels in the intervertebral discs of New Zealand white rabbits under simulated overload and microgravity conditions, focusing on the expression of MMP1, MMP3,...

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Bibliographic Details
Published in:Journal of Orthopaedic Surgery and Research
Main Authors: Xuanyu Chen, Zhangfu Li, Chao Zheng, Ji Wu, Yong Hai
Format: Article
Language:English
Published: BMC 2025-01-01
Subjects:
Overload
Microgravity conditions
Intervertebral disc degeneration
Matrix metalloproteinases
Tissue inhibitor of metalloproteinase
Online Access:https://doi.org/10.1186/s13018-025-05508-6

Internet

https://doi.org/10.1186/s13018-025-05508-6

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