Limited Short-Term Evolution of SARS-CoV-2 RNA-Dependent RNA Polymerase under Remdesivir Exposure in Upper Respiratory Compartments

Background: The extent of the SARS-CoV-2 short-term evolution under Remdesivir (RDV) exposure and whether it varies across different upper respiratory compartments are not fully understood. Methods: Patients hospitalized for COVID-19, with or without RDV therapy, were enrolled and completed up to th...

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Bibliographic Details

Published in:	Viruses
Main Authors:	Vladimir Novitsky, Curt G. Beckwith, Kristin Carpenter-Azevedo, Jimin Shin, Joel Hague, Soya Sam, Jon Steingrimsson, Richard C. Huard, Kevin Lethbridge, Sujata Sahu, Kim Rapoza, Karen Chandran, Lauri Bazerman, Evelyn Hipolito, Isabella Diaz, Daniella Carnevale, August Guang, Fizza Gillani, Angela M. Caliendo, Rami Kantor
Format:	Article
Language:	English
Published:	MDPI AG 2024-09-01
Subjects:	SARS-CoV-2 RdRp remdesivir respiratory compartments drug resistance
Online Access:	https://www.mdpi.com/1999-4915/16/10/1511