Genetic signatures of exceptional longevity: a comprehensive analysis of coding region single nucleotide polymorphisms (SNPs) in centenarians and supercentenarians

Abstract Aging, a complex biological process, entails sequential changes in organisms that elevate the risk of frailty, disease, and mortality, affecting individuals at the level of cellular, organ, and organism. This process is influenced by genetic diversity, socioeconomic status, healthcare infra...

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Bibliographic Details

Published in:	Human Genomics
Main Authors:	Audre Preena Maria Sundar Raj, Gayathri Selvakumar, James Clement, George M. Church, Sudhakar Sivasubramaniam
Format:	Article
Language:	English
Published:	BMC 2025-10-01
Subjects:	Longevity Centenarians and supercentenarians Genomic analysis SNPs Novel genetic variants
Online Access:	https://doi.org/10.1186/s40246-025-00772-3