The effect of amycretin, a unimolecular glucagon-like peptide-1 and amylin receptor agonist, on body weight and metabolic dysfunction in mice and ratsResearch in context

Summary: Background: Amycretin is a novel unimolecular glucagon-like peptide-1 (GLP-1) and amylin receptor agonist. This study aimed to determine its role in mitigating diet-induced metabolic disorders, such as obesity, insulin resistance, and fatty liver disease, in mice and rats. Methods: Preclin...

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Bibliographic Details

Published in:	EBioMedicine
Main Authors:	Rune Ehrenreich Kuhre, Borja Ballarín-González, Christian Lehn Brand, Tine Glendorf, Kim Grimstrup Madsen, Karina Rahr Hjøllund, Wouter Frederik Johan Hogendorf, David Højland Ipsen, Sofia Lundh, Thomas Kruse, Signe Beck Petersen, Anna Secher, Andreas Vegge, Kirsten Raun
Format:	Article
Language:	English
Published:	Elsevier 2025-08-01
Subjects:	Glucagon-like peptide-1 receptor Amylin receptor Metabolism Obesity
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352396425003068