A zebrafish model of acmsd deficiency does not support a prominent role for ACMSD in Parkinson’s disease

Abstract Single nucleotide polymorphisms adjacent to the α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) gene have been associated with Parkinson’s disease (PD) in genome-wide association studies (GWAS). However, its biological validation as a PD risk gene has been hampered by the lac...

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Bibliographic Details

Published in:	npj Parkinson's Disease
Main Authors:	Emma Fargher, Marcus Keatinge, Oluwaseyi Pearce, Petteri Piepponen, Pertti Panula, Fredericus J. M. van Eeden, Ryan B. MacDonald, Oliver Bandmann
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-05-01
Online Access:	https://doi.org/10.1038/s41531-025-00940-1