Single cell RNA analysis of the left–right organizer transcriptome reveals potential novel heterotaxy genes

Abstract The establishment of left–right patterning in mice occurs at a transient structure called the embryonic node or left–right organizer (LRO). Previous analysis of the LRO has proven challenging due to the small cell number and transient nature of this structure. Here, we seek to overcome thes...

Full description

Bibliographic Details
Published in:Scientific Reports
Main Authors: Helen M. Bellchambers, Amruta R. Phatak, Mardi J. Nenni, Maria B. Padua, Hongyu Gao, Yunlong Liu, Stephanie M. Ware
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Online Access:https://doi.org/10.1038/s41598-023-36862-2