SVEP1 is an endogenous ligand for the orphan receptor PEAR1

SVEP1 is linked to numerous human diseases, though its disease-promoting mechanism has remained unclear. Here, the authors identify SVEP1 as a ligand for the orphan receptor PEAR1 and provide insight into the role of this interaction in cardiovascular disease.

Bibliographic Details
Published in:Nature Communications
Main Authors: Jared S. Elenbaas, Upasana Pudupakkam, Katrina J. Ashworth, Chul Joo Kang, Ved Patel, Katherine Santana, In-Hyuk Jung, Paul C. Lee, Kendall H. Burks, Junedh M. Amrute, Robert P. Mecham, Carmen M. Halabi, Arturo Alisio, Jorge Di Paola, Nathan O. Stitziel
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Online Access:https://doi.org/10.1038/s41467-023-36486-0

Internet

https://doi.org/10.1038/s41467-023-36486-0

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