Multi-omics investigation of spontaneous T2DM macaque emphasizes gut microbiota could up-regulate the absorption of excess palmitic acid in the T2DM progression

Although gut microbiota and lipid metabolites have been suggested to be closely associated with type 2 diabetes mellitus (T2DM), the interactions between gut microbiota, lipid metabolites, and the host in T2DM development remains unclear. Rhesus macaques may be the best animal model to investigate t...

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Bibliographic Details

Published in:	eLife
Main Authors:	Xu Liu, Yuchen Xie, Shengzhi Yang, Cong Jiang, Ke Shang, Jinxia Luo, Lin Zhang, Gang Hu, Qinghua Liu, Bisong Yue, Zhenxin Fan, Zhanlong He, Jing Li
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2025-08-01
Subjects:	spontaneous T2DM macaques multi-omics gut microbiota palmitic acid fecal microbiota transplantation
Online Access:	https://elifesciences.org/articles/104355