Evaluating Hemagglutination Inhibition Antibody Titers as a Correlate of Protection for Influenza: A Sensitivity Analysis Based on Information Theory and Causal Inference

Introduction: Identifying hemagglutination inhibition (HI) antibody titers as a key immune correlate of protection (CoP) is crucial for developing, licensing, and monitoring the ongoing effectiveness of new influenza vaccines. Using a new statistical methodology, we explored the link between an inac...

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Bibliographic Details

Published in:	Journal of Global Infectious Diseases
Main Authors:	Fenny Ong, Geert Molenberghs, Andrea Callegaro, Wim Van Der Elst, Geert Verbeke, Florian Stijven, Ingrid Van Keilegom, Ariel Alonso Abad
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2025-01-01
Subjects:	causal inference correlate of protection hemagglutination inhibition antibody titer information theory reverse transcription-polymerase chain reaction-confirmed influenza surrogate
Online Access:	https://journals.lww.com/10.4103/jgid.jgid_89_24