Enhanced meropenem activity and stability following load in Polyvinyl alcohol nanofiber scaffolds with sitagliptin as quorum sensing inhibitor on Pseudomonas aeruginosa

Abstract Background The increasing resistance of bacteria to conventional antibiotics poses a significant health challenge. Innovative strategies, such as combining antibiotics with agents like quorum sensing inhibitors (QSIs), have been developed to combat this issue. QSIs enhance antibiotic effica...

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Bibliographic Details
Published in:Journal of Biological Engineering
Main Authors: Abdelrahman A. Mohsen, Taghrid S. El-Mahdy, Mohamed Emara, Samar A. Salim
Format: Article
Language:English
Published: BMC 2025-08-01
Subjects:
Nanofibers
Sitagliptin
Meropenem
Antibacterial activity
Electrospinner
Online Access:https://doi.org/10.1186/s13036-025-00549-1

Internet

https://doi.org/10.1186/s13036-025-00549-1

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