Patient-specific primary and pluripotent stem cell-derived stromal cells recapitulate key aspects of arrhythmogenic cardiomyopathy

Abstract Primary cardiac mesenchymal stromal cells (C-MSCs) can promote the aberrant remodeling of cardiac tissue that characterizes arrhythmogenic cardiomyopathy (ACM) by differentiating into adipocytes and myofibroblasts. These cells’ limitations, including restricted access to primary material an...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Angela Serena Maione, Viviana Meraviglia, Lara Iengo, Martina Rabino, Mattia Chiesa, Valentina Catto, Claudio Tondo, Giulio Pompilio, Milena Bellin, Elena Sommariva
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-09-01
Online Access:	https://doi.org/10.1038/s41598-023-43308-2