Magnetic Gold Nanoparticle-Labeled Heparanase Monoclonal Antibody and its Subsequent Application for Tumor Magnetic Resonance Imaging

Abstract Heparanase (HPA) is ubiquitously expressed in various metastatic malignant tumors; previous studies have demonstrated that HPA was a potential tumor-associated antigen (TAA) for tumor immunotherapy. We sought to evaluate the feasibility of HPA as a common TAA for magnetic resonance imaging...

Full description

Bibliographic Details

Published in:	Nanoscale Research Letters
Main Authors:	Ning Li, Meng-Meng Jie, Min Yang, Li Tang, Si-Yuan Chen, Xue-Mei Sun, Bo Tang, Shi-Ming Yang
Format:	Article
Language:	English
Published:	SpringerOpen 2018-04-01
Subjects:	Heparanase Monoclonal antibody Molecular imaging Magnetic gold nanoparticle Magnetic resonance imaging
Online Access:	http://link.springer.com/article/10.1186/s11671-018-2518-1