RNA methyltransferase NSUN2-mediated m5C methylation promotes Cr(VI)-induced malignant transformation and lung cancer by accelerating metabolism reprogramming

Hexavalent chromium [Cr(VI)], one common environmental contaminant, has long been recognized as a carcinogen associated with lung cancer, but roles and mechanisms of Cr(VI)-induced epigenetic dysregulations in carcinogenesis remain to be investigated. In this study, we identified that RNA m5C methyl...

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出版年:	Environment International
主要な著者:	Rui-Ke Zhang, Yan Li, Fan-Li Sun, Zhi-Hao Zhou, Yun-Xia Xie, Wen-Jing Liu, Wei Wang, Jian-Ge Qiu, Bing-Hua Jiang, Lin Wang
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2024-10-01
主題:	Hexavalent chromium NSUN2 Cell malignant transformation Metabolic reprogramming Tumor growth
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S016041202400641X