Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells.

We have characterized the biological functions of the chromatin remodeling protein Bptf (Bromodomain PHD-finger Transcription Factor), the largest subunit of NURF (Nucleosome Remodeling Factor) in a mammal. Bptf mutants manifest growth defects at the post-implantation stage and are reabsorbed by E8....

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Published in:PLoS Genetics
Main Authors: Joseph Landry, Alexei A Sharov, Yulan Piao, Lioudmila V Sharova, Hua Xiao, Eileen Southon, Jennifer Matta, Lino Tessarollo, Ying E Zhang, Minoru S H Ko, Michael R Kuehn, Terry P Yamaguchi, Carl Wu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-10-01
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000241&type=printable