Structural basis of coronavirus E protein interactions with human PALS1 PDZ domain
Airah Javorsky et al. present the crystal structures of SARS-CoV-1 and SARS-CoV-2 E proteins in complex with the PALS1 PDZ domain. Their results suggest that the coronavirus E protein can interfere with normal PALS1 binding, potentially disrupting epithelial tissue integrity, and may provide future...
| Published in: | Communications Biology |
|---|---|
| Main Authors: | , , |
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2021-06-01
|
| Online Access: | https://doi.org/10.1038/s42003-021-02250-7 |