Smart Approach for the Design of Highly Selective Aptamer-Based Biosensors

Aptamers are chemically synthesized single-stranded DNA or RNA oligonucleotides widely used nowadays in sensors and nanoscale devices as highly sensitive biorecognition elements. With proper design, aptamers are able to bind to a specific target molecule with high selectivity. To date, the systemati...

Full description

Bibliographic Details

Published in:	Biosensors
Main Authors:	Ali Douaki, Denis Garoli, A. K. M. Sarwar Inam, Martina Aurora Costa Angeli, Giuseppe Cantarella, Walter Rocchia, Jiahai Wang, Luisa Petti, Paolo Lugli
Format:	Article
Language:	English
Published:	MDPI AG 2022-07-01
Subjects:	aptamer aptasensor biosensor machine learning molecular dynamic simulation in silico design
Online Access:	https://www.mdpi.com/2079-6374/12/8/574