BM-MSCs display altered gene expression profiles in B-cell acute lymphoblastic leukemia niches and exert pro-proliferative effects via overexpression of IFI6

Abstract Background The tumor microenvironment (TME) is a supportive environment responsible for promoting the growth and proliferation of tumor cells. Current studies have revealed that the bone marrow mesenchymal stem cells (BM-MSCs), a type of crucial stromal cells in the TME, can promote the mal...

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出版年:	Journal of Translational Medicine
主要な著者:	Chengyun Pan, Tianzhen Hu, Ping Liu, Dan Ma, Shuyun Cao, Qin Shang, Luxin Zhang, Qingzhen Chen, Qin Fang, Jishi Wang
フォーマット:	論文
言語:	英語
出版事項:	BMC 2023-09-01
主題:	B-cell acute lymphoblastic leukemia Tumor microenvironment Mesenchymal stem cells Interferon alpha-inducible protein 6 Proliferation
オンライン･アクセス:	https://doi.org/10.1186/s12967-023-04464-1