Transcriptional control of retinal ganglion cell death after axonal injury

Abstract Injury to the axons of retinal ganglion cells (RGCs) is a key pathological event in glaucomatous neurodegeneration. The transcription factors JUN (the target of the c-Jun N-terminal kinases, JNKs) and DDIT3/CHOP (a mediator of the endoplasmic reticulum stress response) have been shown to co...

Full description

Bibliographic Details

Published in:	Cell Death and Disease
Main Authors:	Stephanie B. Syc-Mazurek, Hongtian Stanley Yang, Olivia J. Marola, Gareth R. Howell, Richard T. Libby
Format:	Article
Language:	English
Published:	Nature Publishing Group 2022-03-01
Online Access:	https://doi.org/10.1038/s41419-022-04666-3