Pharmacokinetic study of Q808 in rhesus monkey using liquid chromatography–tandem mass spectrometry

BackgroundQ808 is a novel antiepileptic agent currently in development. In this study, we established and validated a LC-MS/MS method for the quantification of Q808 in Rhesus monkey plasma. Furthermore, we applied this method to investigate the pharmacokinetics of Q808 in Rhesus monkeys.MethodsSampl...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Ning Xiao, Xiang Li, Wei Li, Jialin Zhao, Yingnan Li, Limei Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-07-01
Subjects:	epilepsy Q808 LC-MS/MS pharmacokinetic rhesus monkeys
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2024.1433043/full