New perspective on the pathophysiology of panic: merging serotonin and opioids in the periaqueductal gray

Panic disorder patients are vulnerable to recurrent panic attacks. Two neurochemical hypotheses have been proposed to explain this susceptibility. The first assumes that panic patients have deficient serotonergic inhibition of neurons localized in the dorsal periaqueductal gray matter of the midbrai...

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Bibliographic Details

Published in:	Brazilian Journal of Medical and Biological Research
Main Author:	F.G. Graeff
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2012-04-01
Subjects:	Panic Animal model Periaqueductal gray Serotonin Opioids
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000400011