Automated Electrophysiology Makes the Pace for Cardiac Ion Channel Safety Screening

The field of automated patch-clamp electrophysiology has emerged from the tension between the pharmaceutical industry’s need for high-throughput compound screening versus its need to be conservative due to regulatory requirements. On the one hand, hERG channel screening was increasingly requested fo...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Clemens eMoeller, Harry eWitchel
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2011-11-01
Subjects:	Torsades de Pointes cardiomyocyte stem cell hERG action potential Automated Patch-Clamp
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fphar.2011.00073/full