Genetic Markers and Danger Signals in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening adverse reactions, which could be induced by a variety of drugs. It was proposed that human leukocyte antigen (HLA)-restricted presentation of antigens (drugs or their metabolites) to T lymphocytes initiates the...

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Bibliographic Details

Published in:	Allergology International
Main Authors:	Wen-Hung Chung, Shuen-Iu Hung
Format:	Article
Language:	English
Published:	Elsevier 2010-01-01
Subjects:	drug hypersensitivity genetic polymorphism NK cells Stevens-Johnson syndrome toxic epidermal necrolysis
Online Access:	http://www.sciencedirect.com/science/article/pii/S1323893015306432