Iron oxide nanozymes stabilize stannous fluoride for targeted biofilm killing and synergistic oral disease prevention

Abstract Dental caries is the most common human disease caused by oral biofilms despite the widespread use of fluoride as the primary anticaries agent. Recently, an FDA-approved iron oxide nanoparticle (ferumoxytol, Fer) has shown to kill and degrade caries-causing biofilms through catalytic activat...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Yue Huang, Yuan Liu, Nil Kanatha Pandey, Shrey Shah, Aurea Simon-Soro, Jessica C. Hsu, Zhi Ren, Zhenting Xiang, Dongyeop Kim, Tatsuro Ito, Min Jun Oh, Christine Buckley, Faizan Alawi, Yong Li, Paul J. M. Smeets, Sarah Boyer, Xingchen Zhao, Derk Joester, Domenick T. Zero, David P. Cormode, Hyun Koo
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-09-01
Online Access:	https://doi.org/10.1038/s41467-023-41687-8