CLINICAL EFFICACY OF TARGETED THERAPY TOWARDS METASTATIC LUNG CANCER CARRYING DISTINCT TYPES OF ALK REARRANGEMENTS

Introduction. Translocations of ALK receptor tyrosine kinase occur in approximately 5–9 % of lung adenocarcinomas. The use of ALK inhibitors usually results in the reduction of tumor size. Nevertheless, the extent and duration of response can vary significantly. The aim of the study is to summarize...

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Bibliographic Details

Published in:	Сибирский онкологический журнал
Main Authors:	N. V. Mitiushkina, I. A. Stepanov, D. O. Yurlov, E. A. Filippova, S. V. Odintsova, A. M. Lozhkina, S. V. Orlov, A. G. Iyevleva
Format:	Article
Language:	Russian
Published:	Russian Academy of Sciences, Tomsk National Research Medical Center 2020-09-01
Subjects:	lung cancer alk translocation crizotinib ceritinib alectinib
Online Access:	https://www.siboncoj.ru/jour/article/view/1539