Cutaneous nociceptors lack sensitisation, but reveal μ-opioid receptor-mediated reduction in excitability to mechanical stimulation in neuropathy

<p>Abstract</p> <p>Background</p> <p>Peripheral nerve injuries often trigger a hypersensitivity to tactile stimulation. Behavioural studies demonstrated efficient and side effect-free analgesia mediated by opioid receptors on peripheral sensory neurons. However, mechani...

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Bibliographic Details

Published in:	Molecular Pain
Main Authors:	Schmidt Yvonne, Labuz Dominika, Heppenstall Paul A, Machelska Halina
Format:	Article
Language:	English
Published:	SAGE Publishing 2012-11-01
Subjects:	Neuropathic pain Nociceptors Mechanical sensitivity Opioids
Online Access:	http://www.molecularpain.com/content/8/1/81