From mechanisms to therapies: current advances breakthroughs in alopecia areata immunopathology

Alopecia areata (AA) is a prevalent autoimmune condition characterized by hair loss, with the collapse of hair follicle immune privilege being a pivotal event in its pathogenesis. This collapse involves intricate immunological disturbances, where CD8+NKG2D+ T cells, driven by inflammatory cytokines...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Huai-Bo Zhao, Ya-Nan Zhang, Yan Qiang, Guo-Mi Wang, Li-Wei Wang, Wen-Cheng Jiang, Xi Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-09-01
Subjects:	alopecia areata hair follicle immune privilege collapse autoimmune immunotherapy targeted therapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1621492/full