ROS-Mediated Necroptosis Promotes Coxsackievirus B3 Replication and Myocardial Injury

Coxsackievirus B3 (CVB3) is a primary causative agent of viral myocarditis (VMC), which can lead to both acute and chronic cardiac inflammation accompanied by progressive heart failure and arrhythmias. Although CVB3 has been implicated in various forms of programmed cell death, whether it triggers n...

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Bibliographic Details
Published in:Microorganisms
Main Authors: Junbo Huang, Yanjun Di, Qing Song, Zhiyun Cheng, Hao Wu, Mei Wu, Minjian He, Genrui Zhang, Fucai Wang, Lei Tong
Format: Article
Language:English
Published: MDPI AG 2025-10-01
Subjects:
coxsackievirus B3
viral myocarditis
necroptosis
RIP1
RIP3
ROS
Online Access:https://www.mdpi.com/2076-2607/13/10/2389

Internet

https://www.mdpi.com/2076-2607/13/10/2389

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