Modulatory impact of Bifidobacterium longum subsp. longum BL21 on the gut–brain–ovary axis in polycystic ovary syndrome: insights into metabolic regulation, inflammation mitigation, and neuroprotection

ABSTRACT This study evaluates the efficacy of Bifidobacterium longum subsp. longum BL21 in mitigating symptoms of polycystic ovarian syndrome (PCOS) in DHT-induced PCOS model mice. It focuses on BL21’s role in modulating metabolic dysregulation, inflammation, and neuroprotection via the gut–brain–ov...

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Bibliographic Details

Published in:	mSphere
Main Authors:	Yao Dong, Shengnan Yang, Shu Zhang, Yuan Zhao, Xinlan Li, Mei Han, Zhonghui Gai, Kang Zou
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-02-01
Subjects:	polycystic ovarian syndrome Bifidobacterium longum subsp. longum gut–brain–ovary axis inflammation mitigation metabolic regulation
Online Access:	https://journals.asm.org/doi/10.1128/msphere.00887-24