Resistant Hypertension On Treatment (ResHypOT): sequential nephron blockade compared to dual blockade of the renin-angiotensin-aldosterone system plus bisoprolol in the treatment of resistant arterial hypertension – study protocol for a randomized controlled trial

Abstract Background Resistant hypertension is characterized when the blood pressure (BP) remains above the recommended goal after taking three antihypertensive drugs with synergistic actions at their maximum recommended tolerated doses, preferably including a diuretic. Identifying the contribution o...

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Bibliographic Details

Published in:	Trials
Main Authors:	Elizabeth do Espirito Santo Cestário, Letícia Aparecida Barufi Fernandes, Luiz Tadeu Giollo-Júnior, Jéssica Rodrigues Roma Uyemura, Camila Suemi Sato Matarucco, Manoel Idelfonso Paz Landim, Luciana Neves Cosenso-Martin, Lúcia Helena Bonalume Tácito, Heitor Moreno Jr., José Fernando Vilela-Martin, Juan Carlos Yugar-Toledo
Format:	Article
Language:	English
Published:	BMC 2018-02-01
Subjects:	Resistant hypertension Natriuretic agents Dual blockade of the renin-angiotensin system Bisoprolol
Online Access:	http://link.springer.com/article/10.1186/s13063-017-2343-3