Engineering of <i>Saccharomyces cerevisiae</i> for 24-Methylene-Cholesterol Production

24-Methylene-cholesterol is a necessary substrate for the biosynthesis of physalin and withanolide, which show promising anticancer activities. It is difficult and costly to prepare 24-methylene-cholesterol via total chemical synthesis. In this study, we engineered the biosynthesis of 24-methylene-c...

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Bibliographic Details
Published in:Biomolecules
Main Authors: Jiao Yang, Changfu Li, Yansheng Zhang
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Subjects:
Online Access:https://www.mdpi.com/2218-273X/11/11/1710