Appraising the causal relationship between plasma caffeine levels and neuropsychiatric disorders through Mendelian randomization

Abstract Background Caffeine exposure modifies the turnover of monoamine neurotransmitters, which play a role in several neuropsychiatric disorders. We conducted a Mendelian randomization study to investigate whether higher plasma caffeine levels are causally associated with the risk of anorexia ner...

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Bibliographic Details

Published in:	BMC Medicine
Main Authors:	Benjamin Woolf, Héléne T. Cronjé, Loukas Zagkos, Stephen Burgess, Dipender Gill, Susanna C. Larsson
Format:	Article
Language:	English
Published:	BMC 2023-08-01
Subjects:	Anorexia nervosa Bipolar disorder caffeine Coffee Depression Mendelian randomization Schizophrenia
Online Access:	https://doi.org/10.1186/s12916-023-03008-0