Comparative effectiveness and safety of tenecteplase versus alteplase for intravenous thrombolysis in acute ischemic stroke: a retrospective study

BackgroundTenecteplase has been proposed as a practical alternative to alteplase for intravenous thrombolysis in acute ischemic stroke. Although randomised trials have demonstrated noninferiority, data from real-world comparative cohorts remain limited.AimThis study evaluated functional and safety o...

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Bibliographic Details

Published in:	Frontiers in Neurology
Main Authors:	Weili Zhao, Xi Zhang, Yang Zhao, Ruijie Zhao, Yalin Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	tenecteplase alteplase intravenous thrombolysis acute ischemic stroke stroke
Online Access:	https://www.frontiersin.org/articles/10.3389/fneur.2025.1691168/full