Co-localization of clusters of TCR-regulated genes with TAD rearrangements

Abstract Background Gene expression has long been known to be influenced by the relative proximity of DNA regulatory elements. Topologically associating domains (TADs) are self-interacting genomic regions involved in regulating gene expression by controlling the proximity of these elements. Prior st...

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Bibliographic Details
Published in:BMC Genomics
Main Authors: Galen F. Gao, Peng Li, Warren J. Leonard
Format: Article
Language:English
Published: BMC 2023-10-01
Subjects:
TADs
Chromatin conformation
Epigenetics
Gene expression
Immunoinformatics
Multi-omics
Online Access:https://doi.org/10.1186/s12864-023-09693-8

Internet

https://doi.org/10.1186/s12864-023-09693-8

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