Co-localization of clusters of TCR-regulated genes with TAD rearrangements

Abstract Background Gene expression has long been known to be influenced by the relative proximity of DNA regulatory elements. Topologically associating domains (TADs) are self-interacting genomic regions involved in regulating gene expression by controlling the proximity of these elements. Prior st...

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Bibliographic Details
Published in:	BMC Genomics
Main Authors:	Galen F. Gao, Peng Li, Warren J. Leonard
Format:	Article
Language:	English
Published:	BMC 2023-10-01
Subjects:	TADs Chromatin conformation Epigenetics Gene expression Immunoinformatics Multi-omics
Online Access:	https://doi.org/10.1186/s12864-023-09693-8

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