STING regulates NETs formation by activating GSDMD in influenza viral pneumonia

BackgroundViral pneumonia is the most common and lethal pandemic disease, but there are no broad-spectrum antiviral drugs with high genetic barriers to resistance. To elucidate the mechanisms of viral pneumonia progression and potential targets for its treatment.MethodsViral pneumonia models were in...

Full description

Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Rongrong Huang, Ranran Chen, Lijuan Xing, Lianhao Wu, Wenwen Zhu, Junsong Jing, Ting Zhou, Yueguo Wu, Sheng Zhang, Zhenqiang You
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-07-01
Subjects:	viral pneumonia STING NETs GSDMD anti-inflammatory
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1598902/full