Neuroprotection by chronic administration of Fluoroethylnormemantine (FENM) in mouse models of Alzheimer's disease

Abstract Background Fluoroethylnormemantine (FENM), a new Memantine (MEM) derivative, prevented amyloid-β[25–35] peptide (Aβ25–35)-induced neurotoxicity in mice, a pharmacological model of Alzheimer's disease (AD) with high predictive value for drug discovery. Here, as drug infusion is likely t...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Alzheimer’s Research & Therapy
المؤلفون الرئيسيون: Allison Carles, Aline Freyssin, Sarra Guehairia, Thomas Reguero, Michel Vignes, Hélène Hirbec, Gilles Rubinstenn, Tangui Maurice
التنسيق: مقال
اللغة:الإنجليزية
منشور في: BMC 2025-01-01
الموضوعات:
Fluoroethylnormemantine (FENM)
Alzheimer's disease
Drug infusion
Neuroprotection
NMDA receptor expression
الوصول للمادة أونلاين:https://doi.org/10.1186/s13195-024-01648-9

الانترنت

https://doi.org/10.1186/s13195-024-01648-9

مواد مشابهة