HNRNPC stabilizes m6A-modified AC145207.5 to accelerate tumorigenesis in colorectal cancer by impeding the Nrf2/GPX4 axis-mediated ferroptosis

Ferroptosis is an apoptosis-independent cell death pathway characterized by heightened lipid peroxidation, which shows promise for tumor suppression. Despite extensive research on long non-coding RNAs (LncRNAs) in ferroptosis, their role in colorectal cancer (CRC) remains underexplored. We investiga...

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Bibliographic Details

Published in:	Non-coding RNA Research
Main Authors:	Dan Liu, Shanshan Lin, Yueben Hu, Jianyong Xiong, Hongtao Wan, Yanglin Chen, Taohui Ding, Hu Zhao, Renjie Jiang, Zhijiang Huang, Dengke Yao, Ming Li, Xiaojian Zhu, Bo Yi
Format:	Article
Language:	English
Published:	KeAi Communications Co., Ltd. 2025-08-01
Subjects:	m6A RNA binding protein Ferroptosis Nrf2/GPX4 signaling pathway
Online Access:	http://www.sciencedirect.com/science/article/pii/S2468054025000411