Exercise ameliorates muscular excessive mitochondrial fission, insulin resistance and inflammation in diabetic rats via irisin/AMPK activation

Abstract This study aimed to investigate the effects of exercise on excessive mitochondrial fission, insulin resistance, and inflammation in the muscles of diabetic rats. The role of the irisin/AMPK pathway in regulating exercise effects was also determined. Thirty-two 8-week-old male Wistar rats we...

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Bibliographic Details
Published in:Scientific Reports
Main Authors: Junjie Lin, Xin Zhang, Yu Sun, Haocheng Xu, Nan Li, Yuanxin Wang, Xin Tian, Chen Zhao, Bin Wang, Baishu Zhu, Renqing Zhao
Format: Article
Language:English
Published: Nature Portfolio 2024-05-01
Subjects:
Exercise training
Irisin
Mitochondrial fission
Inflammation
Diabetes
Online Access:https://doi.org/10.1038/s41598-024-61415-6

Internet

https://doi.org/10.1038/s41598-024-61415-6

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