Octreotide Conjugates for Tumor Targeting and Imaging

Tumor targeting has emerged as an advantageous approach to improving the efficacy and safety of cytotoxic agents or radiolabeled ligands that do not preferentially accumulate in the tumor tissue. The somatostatin receptors (SSTRs) belong to the G-protein-coupled receptor superfamily and they are ove...

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Bibliographic Details
Published in:Pharmaceutics
Main Authors: Eduard Figueras, Ana Martins, Adina Borbély, Vadim Le Joncour, Paola Cordella, Raffaella Perego, Daniela Modena, Paolo Pagani, Simone Esposito, Giulio Auciello, Marcel Frese, Paola Gallinari, Pirjo Laakkonen, Christian Steinkühler, Norbert Sewald
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Subjects:
tumor targeting
small molecule drug conjugates
cryptophycin
octreotide
cytotoxic payloads
imaging
Online Access:https://www.mdpi.com/1999-4923/11/5/220

Internet

https://www.mdpi.com/1999-4923/11/5/220

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