IL-17-Dependent Dysregulated Cutaneous Immune Homeostasis in the Absence of the Wiskott–Aldrich Syndrome Protein

Wiskott–Aldrich Syndrome (WAS) is characterized by recurrent infections, thrombocytopenia, and eczema. Here, we show that WASp-deficient mice on a BALB/c background have dysregulated cutaneous immune homeostasis with increased leukocyte accumulation in the skin, 1 week after birth. Increased cutaneo...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Frontiers in Immunology
المؤلفون الرئيسيون: Katherine E. Herman, Takeshi Yoshida, Angela Hughson, Alex Grier, Steven R. Gill, Lisa A. Beck, Deborah J. Fowell
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Frontiers Media S.A. 2022-02-01
الموضوعات:
Wiskott–Aldrich syndrome
skin
immune homeostasis
IL-17
inflammation
الوصول للمادة أونلاين:https://www.frontiersin.org/articles/10.3389/fimmu.2022.817427/full

الانترنت

https://www.frontiersin.org/articles/10.3389/fimmu.2022.817427/full

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