Single-cell transcriptional analysis reveals allergen-specific signatures in human γδ T cells

The role of gamma-delta T (γδ T) cells in immune responses to common allergens is poorly understood. Here, we utilized single-cell (sc) transcriptomic analysis of allergen-reactive γδ T cells in humans to characterize the transcriptional landscapes and TCR repertoires in response to cockroach (CR) a...

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Bibliographic Details

Published in:	JCI Insight
Main Authors:	Kendall Kearns, Sloan A. Lewis, Esther Dawen Yu, Adam Abawi, Eric Wang, Synaida Maiche, Monalisa Mondal, Pandurangan Vijayanand, Grégory Seumois, Bjoern Peters, Alessandro Sette, Ricardo Da Silva Antunes
Format:	Article
Language:	English
Published:	American Society for Clinical investigation 2025-06-01
Subjects:	Cell biology Immunology
Online Access:	https://doi.org/10.1172/jci.insight.191359