Batch correction and harmonization of –Omics datasets with a tunable median polish of ratio

Large scale −omics datasets can provide new insights into normal and disease-related biology when analyzed through a systems biology framework. However, technical artefacts present in most −omics datasets due to variations in sample preparation, batching, platform settings, personnel, and other expe...

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Bibliographic Details

Published in:	Frontiers in Systems Biology
Main Authors:	Eric B. Dammer, Nicholas T. Seyfried, Erik C. B. Johnson
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-04-01
Subjects:	batch correction multi-platform multi-cohort proteomics median polish multi-omics
Online Access:	https://www.frontiersin.org/articles/10.3389/fsysb.2023.1092341/full