CD44 correlates with longevity and enhances basal ATF6 activity and ER stress resistance

Summary: The naked mole rat (NMR) is the longest-lived rodent, resistant to multiple age-related diseases including neurodegeneration. However, the mechanisms underlying the NMR’s resistance to neurodegenerative diseases remain elusive. Here, we isolated oligodendrocyte progenitor cells (OPCs) from...

Full description

Bibliographic Details
Published in:Cell Reports
Main Authors: Masaki Takasugi, Naoko Ohtani, Kazuaki Takemura, Stephan Emmrich, Frances T. Zakusilo, Yuya Yoshida, Nobuyuki Kutsukake, John N. Mariani, Martha S. Windrem, Devin Chandler-Militello, Steven A. Goldman, Junko Satoh, Shinji Ito, Andrei Seluanov, Vera Gorbunova
Format: Article
Language:English
Published: Elsevier 2023-09-01
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723011427