Acetylation reprograms MITF target selectivity and residence time

Abstract The ability of transcription factors to discriminate between different classes of binding sites associated with specific biological functions underpins effective gene regulation in development and homeostasis. How this is achieved is poorly understood. The microphthalmia-associated transcri...

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التفاصيل البيبلوغرافية
الحاوية / القاعدة:Nature Communications
المؤلفون الرئيسيون: Pakavarin Louphrasitthiphol, Alessia Loffreda, Vivian Pogenberg, Sarah Picaud, Alexander Schepsky, Hans Friedrichsen, Zhiqiang Zeng, Anahita Lashgari, Benjamin Thomas, E. Elizabeth Patton, Matthias Wilmanns, Panagis Filippakopoulos, Jean-Philippe Lambert, Eiríkur Steingrímsson, Davide Mazza, Colin R. Goding
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Nature Portfolio 2023-09-01
الوصول للمادة أونلاين:https://doi.org/10.1038/s41467-023-41793-7

الانترنت

https://doi.org/10.1038/s41467-023-41793-7

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