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Discovery and characterization of novel potent non-covalent small molecule inhibitors targeting papain-like protease from SARS-CoV-2

Bibliographic Details
Published in:Acta Pharmaceutica Sinica B
Main Authors: Miao Zheng, Bo Feng, Yumin Zhang, Xin Liu, Na Zhao, Hui Liu, Zichao Xu, Xinheng He, Zhiyan Qu, Shizhao Chen, Zhidong Jiang, Xi Cheng, Hong Liu, Yi Zang, Linxiang Zhao, Jie Zheng, Leike Zhang, Jia Li, Yu Zhou
Format: Article
Language:English
Published: Elsevier 2024-07-01
Subjects:
Non-covalent PLpro inhibitors
Antiviral activity
Structural-based drug design
Imidazo[4,5-b]pyridine scaffold
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383524001400
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http://www.sciencedirect.com/science/article/pii/S2211383524001400

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