JTT-553, a novel Acyl CoA:diacylglycerol acyltransferase (DGAT) 1 inhibitor, improves glucose metabolism in diet-induced obesity and genetic T2DM mice

Type 2 diabetes mellitus (T2DM) arises primarily due to lifestyle factors and genetics. A number of lifestyle factors are known to be important in the development of T2DM, including obesity. JTT-553, a novel Acyl CoA:diacylglycerol acyltransferase 1 inhibitor, reduced body weight depending on dietar...

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發表在:	Journal of Pharmacological Sciences
Main Authors:	Daisuke Tomimoto, Chihiro Okuma, Yukihito Ishii, Akio Kobayashi, Takeshi Ohta, Makoto Kakutani, Tsuneo Imanaka, Nobuya Ogawa
格式:	Article
語言:	英语
出版:	Elsevier 2015-09-01
主題:	Obesity Type 2 diabetes Insulin resistance Triacylglycerol Acyl CoA:diacylglycerol acyltransferase (DGAT) 1
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S1347861315001802