Role of protein kinases JNK and p38 in regulation of mononuclear leucocytes apoptosis in oxidative stress

Programmed cell death of peripheral blood mononuclear leucocytes taken from healthy donors and cultivated with various concentration of Н2О2, selective inhibitors of JNK (SP600125), 38 (ML3403) and in case of pneumonia was investigated. Intensification of intracellular production of reactive oxy р М...

Full description

Bibliographic Details

Published in:	Бюллетень сибирской медицины
Main Author:	N. Yu. Chasovskikh
Format:	Article
Language:	English
Published:	Siberian State Medical University (Tomsk) 2008-09-01
Subjects:	oxidative stress apoptosis mitogen-activated protein kinases (jnk, p38) mitochondria tnf-receptor
Online Access:	https://bulletin.ssmu.ru/jour/article/view/3492