Early-life adversity and long-term neurobehavioral outcomes: epigenome as a bridge?

Abstract Accumulating evidence suggests that adversities at critical periods in early life, both pre- and postnatal, can lead to neuroendocrine perturbations, including hypothalamic-pituitary-adrenal axis dysregulation and inflammation persisting up to adulthood. This process, commonly referred to a...

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Bibliographic Details

Published in:	Human Genomics
Main Authors:	Alexander M. Vaiserman, Alexander K. Koliada
Format:	Article
Language:	English
Published:	BMC 2017-12-01
Subjects:	Biological embedding DNA methylation Early-life adversity Epigenetics Neurobehavioral outcomes
Online Access:	http://link.springer.com/article/10.1186/s40246-017-0129-z