The Comparative Effectiveness and Tolerability of Sphingosine‐1‐Phosphate Receptor Modulators in Patients With Multiple Sclerosis: A Network Meta‐Analysis of Randomized Controlled Trials

ABSTRACT Background Sphingosine‐1‐phosphate receptor modulators (S1PRM) are used to treat relapsing multiple sclerosis (MS). Each drug has a different S1PR‐subtype selectivity. They target the G‐protein coupled S1P receptors and exert significant immunomodulatory effects, such as preventing the form...

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Bibliographic Details
Published in:Annals of Clinical and Translational Neurology
Main Authors: Faizan Shahzad, Taimoon Rasheed, Momina Riaz Siddiqui, Hamza Hamid, Marwah Bintay Khalid, Haroon Shabbir, Besher Shami, Abdullah, Syed Ijlal Ahmed
Format: Article
Language:English
Published: Wiley 2025-10-01
Subjects:
multiple sclerosis
network meta‐analysis
sphingosine‐1‐phosphate receptor modulators
Online Access:https://doi.org/10.1002/acn3.70122

Internet

https://doi.org/10.1002/acn3.70122

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