Mutations in the “hot spots” of the <i>FLT3</i>, <i>NPM1</i>, <i>IDH1</i>, <i>IDH2</i> and <i>DNMT3A</i> genes in acute myeloid leukemia

The purpose of the study was to systematize and present up-to-date data on the prevalence, combination and clinical significance of mutations in the “hot spots” of the FLT3, NPM1, IDH1, IDH2, DNMT3A genes in acute myeloid leukemia (AML). Material and methods. A search was conducted for available dom...

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Bibliographic Details

Published in:	Сибирский онкологический журнал
Main Authors:	E. N. Voropaeva, M. V. Burundukova, A. A. Lyzlova, I. A. Chukhontseva, V. N. Maksimov, T. I. Pospelova
Format:	Article
Language:	Russian
Published:	Russian Academy of Sciences, Tomsk National Research Medical Center 2025-03-01
Subjects:	acute myeloid leukemia clonal evolution mutation hotspots <i>npm1</i> <i>idh1</i> <i>idh2</i> <i>flt3</i> <i>dnmt3a</i> prognosis minimal residual disease targeted treatment
Online Access:	https://www.siboncoj.ru/jour/article/view/3458